CASCADE Research Projects

Recent/Ongoing Research Projects

Designing Nature to Enhance Resilience of Built Infrastructure in Western U.S. Landscape Nature-Based Solutions Project Site
US Army Corps of Engineers (USACE)

This research advances Engineering With Nature approaches by integrating natural systems into traditional built infrastructure to improve resilience of water systems across the western United States. The project broadens the definition of natural infrastructure to include diverse natural assets such as wetlands, soils, and forest ecosystems, and develops tools to analyze how combinations of natural and built assets perform under stress. It aims to produce modeling and visualization platforms for scenario-based analysis that can help stakeholders plan portfolios of interoperable natural-built systems. The work aligns hydrologic science, data-driven analysis, and stakeholder engagement to support resilient and equitable water infrastructure planning.

PanAX: Accelerating Epidemic Science through Causally-Informed Domain Generalization and Knowledge Transfer Causal Learning Epidemics
NSF ACED: Track I

The understanding and containment of epidemics involves many factors, such as how people behave and interact, how they move around, and the decisions made by governments and organizations to control the spread. Because of this complexity, building accurate and timely models to predict and manage outbreaks in near real time is challenging and time consuming. It also requires copious data, which are often unavailable when it is urgently needed. To address these challenges, this project develops PanAX, a new computational system to improve how we prepare for and respond to evolving epidemics. The core idea is to use existing data and models in smarter ways and based on situational awareness, so we do not have to start from scratch every time.

CausalBench: A Cyberinfrastructure for Causal-Learning Benchmarking Causal Learning Cyberinfrastructure
NSF Elements

CausalBench develops a transparent, fair, and easy-to-use causal benchmarking platform, aiming to (a) enable the advancement of research in causal learning by facilitating scientific collaboration in novel algorithms, datasets, and metrics and (b) promote scientific objectivity, reproducibility, fairness, and awareness of bias in causal learning research. CausalBench provides services for downloading and exploring benchmarking data, algorithms, models, metrics, and benchmark results.

A Database Architecture for Enhanced Privacy in Machine-Learning Applications Privacy Databases Award Notice
NSF SaTC

This project develops novel database system architectures that embed strong privacy protections into machine learning workflows. The research focuses on creating systems where sensitive information can be processed and analyzed without exposing raw data. By integrating privacy mechanisms at the database level, the project aims to support secure analytics while maintaining performance. This effort bridges database design, security, and machine-learning requirements to protect data in real-world applications.

NSF Center for the Analysis and Prediction of Pandemic Expansion (APPEX) Pandemics Prediction
NSF PIPP Phase II Center

APPEX is a multi-disciplinary NSF center focused on understanding how localized outbreaks evolve into global pandemics through socio-biological and environmental data integration. The center develops predictive models that include biological, social, and information systems to forecast pandemic growth and support decision-making. APPEX engages with public health and policy communities to translate research insights into actionable strategies for anticipation and mitigation. This center also emphasizes education and collaboration across fields to strengthen pandemic preparedness infrastructure.

Building Decarbonization via AI-empowered District Heat Pump Systems Decarbonization AI Systems Award Notice
NSF PIRE

This international project studies AI-enabled control and optimization of district heat pump systems to accelerate equitable and resilient building decarbonization. The project investigates the use of artificial intelligence to optimize district-scale heat pump systems, which are key to reducing carbon emissions in building energy systems. The research combines systems modeling with real-world deployments to improve energy efficiency and decarbonize heating infrastructure. By embedding AI control and optimization, the project aims to enhance operational performance under varying demand and environmental conditions. The work contributes to scalable decarbonization strategies across urban and community energy systems.

Rethink and Redesign of Analytics Databases for ML Model Serving Data Systems Award Notice
NSF CAREER

This NSF CAREER award supports research into redesigning analytics database systems to better support the lifecycle of machine learning model serving. Traditional database systems are optimized for queries, but not for serving ML models at scale; this project seeks to bridge that gap by developing architectural extensions that treat ML models as first-class data and queryable objects. The research aims to unify data management, model execution, and performance optimizations to improve latency, scalability, and integration with broader data ecosystems. An important component is engaging students and developing educational materials that span databases and AI systems.

A Graph Representation Fusing Multi-Modal Data Streams for Enhanced Inference Tasks Graph Learning Multi-Modal Data
NSF Core

This project develops graph-based representations that fuse heterogeneous data streams to improve inference and reasoning in complex systems.

Decision Intelligence System for Causal Exploration and Verification Causal Inference Decision Intelligence
DISCOVER Initiative

DISCOVER develops decision intelligence tools for causal exploration and hypothesis verification using interactive analytics.

Southwest Sustainability Innovation Engine (SWSIE) Sustainability Innovation
NSF Engines

SWSIE is an NSF Engines initiative that accelerates sustainability-driven innovation in the southwestern United States by connecting research with industry, government, and community partners. The program funds interdisciplinary teams tackling challenges in clean energy, water sustainability, climate adaptation, and economic development. By fostering partnerships, SWSIE supports translational research that moves technologies from concept to regional impact, while building workforce capabilities. The engine emphasizes inclusive innovation strategies to strengthen regional resilience and competitiveness.

Recently Completed Projects

PanCommunity: Leveraging Data and Models for Pandemic Response Pandemics
NSF SCC-IRG JST

PanCommunity is a multidisciplinary project that integrates diverse data streams and analytical models to understand and improve how communities respond to pandemics. By combining epidemiological data with social and behavioral insights, the project aims to produce tools that inform public health strategies during disease outbreaks. It emphasizes community-level decision support and resilient response planning. This effort includes engaging stakeholders and translating model outputs into usable guidance for local practitioners.

Building a Heatwave Resilient Community in Arizona Climate Resilience Community
NSF CIVIC-PG Track A

This project focuses on addressing extreme heat hazards by developing strategies and tools to enhance community resilience in Arizona. Researchers work with local stakeholders to understand heat impacts on public health, infrastructure, and social systems. The effort combines climate data, urban planning insights, and community engagement to co-create interventions that reduce heat vulnerability. A key output is actionable guidance that informs policy and resource allocation for heat adaptation.

Getting the Edge on Data-Driven Self-Managed Care for Older Veterans Edge Computing Healthcare
NSF SCC-PG

This project develops edge computing systems that enable privacy-preserving, data-driven self-care tools for older veterans’ health management. The research integrates wearable and sensor data with intelligent analytics at the network edge to support self-management of chronic conditions. Emphasis is on human-centered design, secure data handling, and real-world deployment with veteran populations. The goal is to improve health outcomes while ensuring users’ control over their data.

Predicting Emergence in Multidisciplinary Pandemic Tipping-Points (PREEMPT) Pandemics
NSF PIPP Phase I

PREEMPT explores early detection of pandemic emergence by identifying tipping points in disease spread through combined biological, environmental, and social data. The project develops interdisciplinary models that capture complex interactions leading to pandemic escalation. It seeks to inform early warning systems and response strategies by revealing critical thresholds where small changes could shift outbreak dynamics. This foundational work supports more effective preparedness planning and strategic interventions

Computational Foundations for Bio-Social Modeling of Unseen Pandemics Bio-Social Modeling
NSF PIPP Phase I

This research develops computational frameworks that integrate biological and social processes to model pandemics that have not yet been observed. The project addresses fundamental challenges in representing interactions between pathogen dynamics and human behavior. Results aim to improve prediction of outbreak scenarios and to test intervention strategies in silico. This work provides a basis for understanding complex dependencies in global health risks.

Interdisciplinary Models to Identify and Understand Cyberbullying Cyberbullying
NSF SaTC CORE

This project develops computational and behavioral models to detect and explain cyberbullying behaviors online. It integrates techniques from machine learning, social computing, and human factors to improve identification of harmful interactions. The research emphasizes fairness and context-sensitivity to reduce bias and misclassification. Outputs include models and tools that can support safer online environments and better understanding of social media dynamics.

Self-Adaptive Cyber Risk Management via Machine-to-Machine Economy Cyber Risk Blockchain
NSF SaTC CORE

This project investigates novel frameworks for cyber risk management in interconnected systems where autonomous machines transact and coordinate. By leveraging blockchain and smart contract technologies, the research explores adaptive mechanisms that can dynamically assess and distribute cyber risk. The goal is to support resilient, trust-aware machine-to-machine ecosystems while mitigating vulnerabilities from automated economic behaviors. This work contributes to secure large-scale sociotechnical systems.

pCAR: Discovering Plausibly Causal Relationships in Dynamic Systems Causality
NSF III: Small

pCAR develops methodologies to identify plausible causal links in complex systems where rigorous causal inference is challenging. The project focuses on dynamic environments where interactions evolve over time and traditional causal methods are limited. By integrating statistical learning with dynamic systems theory, the work aims to improve understanding of cause–effect relationships that guide decision-making. The resulting tools are intended to support analysis in socio-technical, biological, and engineered systems.

Earlier Projects

Award Title Originating Sponsor Lead PI
American Express Professorship in Computing American Express Company Elsayed, Mohamed Sarwat Abdelghany Aly 
Models for Dense Urban Areas ASU: ASU Research Enterprise (ASURE) Papotti, Paolo 
CASCADE Project: Intelligent AirPlane: Assessment of Onboard Data Processing Architectures and ML algorithms for pilot in the loop operations ASU: Center for Assured and Scalable Data Engineering (CASCADE) Boscovic, Dragan 
Blockchain Labs: Scalability and Throughput for Digital Currency Networks ASU: Center for Assured and Scalable Data Engineering (CASCADE) Boscovic, Dragan 
Center for Assured and Scalable Data Engineering (CASCADE)-Administrative ASU: Center for Assured and Scalable Data Engineering (CASCADE) Candan, Kasim Selcuk
CASCADE Project: ASSESSING SOFTWARE RISK WITH HACKER COMMUNITYDATA ASU: Center for Assured and Scalable Data Engineering (CASCADE) Shakarian, Paulo 
CASCADE PROJECT: ASSESSING SUPPLY-CHAIN RISK WITH DARKWEB DATA ASU: Center for Assured and Scalable Data Engineering (CASCADE) Shakarian, Paulo 
Blockchain Course Creation Dash Boscovic, Dragan 
Designing nature to enhance resilience of built infrastructure in western US landscapes DOD-ARMY: Army Corps of Engineers (USACE) Muenich, Rebecca Logsdon
COMMERCIALIZATION OF THE SOCIAL INFLUENCE ALGORITHMS FOR INFORMATION OPERATIONS DOD-ARMY: Army Materiel Command (AMC) Shakarian, Paulo 
ASU Decision Theater  TRADOC Partnership DOD-ARMY: Training and Doctrine Command (TRADOC) Miller, Jon 
Securing Grid-interactive Efficient Buildings (GEB) through Cyber Defense and Resilient System (CYDRES) DOE: Office of Energy Efficiency and Renewable Energy (EERE) Wu, Teresa 
Toward new classification criteria for mild and moderate TBI by a data-inclusive cross-study analysis using FITBIR HHS-NIH: National Institute of Child Health & Human Development (NICHD) Li, Jing 
Comprehensive MRI-based evaluation of human renal microstructure HHS-NIH: National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) Wu, Teresa 
Quantifying Multiscale Competitive Landscapes of Clonal Diversity in Glioblastoma HHS: National Institutes of Health (NIH) Li, Jing 
SaTC: CORE: Medium: Self-Adaptive Cyber Risk Management via Machine to Machine Economy supported by blockchain and smart contracts technology National Science Foundation (NSF) Boscovic, Dragan 
SCC-IRG JST: PanCommunity: Leveraging Data and Models for Understanding and Improving Community Response in Pandemics National Science Foundation (NSF) Candan, Kasim Selcuk
III: Small: pCAR: Discovering and Leveraging Plausibly Causal (p-causal) Relationships  to Understand Complex Dynamic Systems National Science Foundation (NSF) Candan, Kasim Selcuk
Research and Educational Activities at IEEE ICDE'19 National Science Foundation (NSF) Candan, Kasim Selcuk
BIGDATA: Collaborative Research: F: Discovering Context-Sensitive Impact in Complex Systems National Science Foundation (NSF) Candan, Kasim Selcuk
CDSECollaboration Research: Datastorm: A DataEnabled System for End-to-End Disaster Planning and Response National Science Foundation (NSF) Candan, Kasim Selcuk
Collaborative Research: Planning Grant: IUCRC for Assured and SCAlable Data Engineering (CASCADE) National Science Foundation (NSF) Candan, Kasim Selcuk
RAPID: Understanding the Evolution Patterns of the Ebola Outbreak in West-Africa and Supporting Real-Time Decision Making and Hypothesis Testing National Science Foundation (NSF) Candan, Kasim Selcuk
SI2-SSE: E-SDMS: Energy Simulation Data Management System Software National Science Foundation (NSF) Candan, Kasim Selcuk
PFI:BIC: Fraud Detection via Visual Analytics: An Infrastructure to Support Complex Financial Patterns (CFP)-based Real-Time Services Delivery National Science Foundation (NSF) Davulcu, Hasan 
III: EAGER: Data Management Systems Support for Personalized Recommendation Applications National Science Foundation (NSF) Elsayed, Mohamed Sarwat Abdelghany Aly 
SaTC: CORE: Medium: Interdisciplinary Models to Identify and Understand Cyberbullying National Science Foundation (NSF) Hall, Deborah L
Collaborative Research: RAPID: RTEM: Rapid Testing as Multi-fidelity Data Collection for Epidemic Modeling National Science Foundation (NSF) Pedrielli, Giulia 
EAGER CMMI OE Exploring Discrete Event Dynamics to model and control intelligent systems National Science Foundation (NSF) Pedrielli, Giulia 
CRISP: Type 2Collaborative Research: Design and Control of Coordinated Green and Gray Water Infrastructure to Improve Resiliency in Chemical and Agri National Science Foundation (NSF) Sabo, John 
RAPID: FACT: Federated Analytics based Contact Tracing for COVID-19 National Science Foundation (NSF) Sankar, Lalitha 
SaTC: CORE: Medium: Interdisciplinary Models to Identify and Understand Cyberbullying National Science Foundation (NSF) Silva, Yasin Nilton
PIPP Phase I: Computational foundations for bio-social modeling of unseen pandemics National Science Foundation (NSF) Turaga, Pavan Kumar
PFI-RP: Building Doctor's Medicine Cabinet (BDMC): Data-Driven Services for High Performance and Sustainable Buildings National Science Foundation (NSF) Wu, Teresa 
PFI-RP: Building Doctor's Medicine Cabinet (BDMC): Data-Driven Services for High Performance and Sustainable Buildings National Science Foundation (NSF) Wu, Teresa 
NRI: FND: Scalable and Customizable Intent Inference and Motion Planning for Socially-Adept Autonomous Vehicles National Science Foundation (NSF) Zhang, Wenlong 
CAREER: Rethink and Redesign of Analytics Databases for Machine Learning Model Serving National Science Foundation (NSF) Zou, Jia 
SCC-Planning: Smart Connected Engaged Senior Communities NSF-CISE: Computer and Network Systems (CNS) Wu, Teresa 
II-New - GEARS - An Infrastructure for Energy-Efficient Big Data Research on Heterogenous and Dynamic Data NSF-CISE: Computer and Network Systems (CNS) Zhao, Ming 
III: Small: Data Management for Real-Time Data Driven Epidemic Spread Simulations NSF: Directorate for Biological Sciences (BIO) Candan, Kasim Selcuk
Blockchain Applied Research Lab (BARC) Partnership for Economic Innovation (AZPEI) Boscovic, Dragan 
JRP-SRP-Blockchain IoT Platform for P2P Energy Transactions Salt River Project (SRP) Boscovic, Dragan 
JRP SRP: Towards a Utility Network Data Management System Salt River Project (SRP) Elsayed, Mohamed Sarwat Abdelghany Aly 
Deep Phenotyping for Physiologic Biomarkers for Post-Traumatic Epilepsy in Children US Department of Defense (DOD) Candan, Kasim Selcuk

CASCADE R&D is supported by funds from several funding agencies, including NSF and DOE, as well as various industrial partners.